coenzyme-q10-research

There is no doubt that everyone deserves to be healthy and feel great. The Coenzyme Q10 has long been touted as one of the world’s best antioxidants and plays a critical role in producing energy, fighting free radicals and promoting general well-being.

What is Ubiquinol?

The enzyme CoQ10 is created naturally within the body. When it is used, the body converts it into its purest free-radical form—Ubiquinol. This substance is absolutely essential for the production of cellular energy, and it is responsible for more than 95 percent of all of the energy produced within the body. In fact, it is often called the world’s greatest energy supplement. At around age 30, the human body is no longer able to produce the enzyme as efficiently as it once did. This means that Ubiquinol production is also significantly hindered, and the body is not as energetic as it once was. Some prescription medications can also greatly reduce the amount of natural Ubiquinol that the body produces. For this reason, many people choose to take these over-the-counter supplements as part of their daily regimen. The body also needs these fat-soluble antioxidant enzymes to fight off free radicals that cause the human body to age much faster and can even cause cancer. When a per
son takes a standard supplement, the body still needs to convert this enzyme into Ubiquinol. This results in some pretty serious energy expenditures and can diminish the effectiveness of the supplement. Ubiquinol supplements are designed to be easily fat-soluble and therefore much easier for the body to use.

Ubiquinol vs CoQ10

Coenzyme Q10 is the natural enzyme that is produced in every single cell of the body to provide energy and fend off cellular breakdown. When this enzyme is used by the body, it is converted into Ubiquinol; this process is absolutely vital to producing antioxidants and creating cellular energy. In young people, this process is as natural as breathing. The body does it very efficiently, so young people rarely experience fatigue or premature aging outside of special health issues. When people reach their 30s, however, the body is no longer able to process this enzyme as efficiently as it once did. Because of this, people often begin to show the first signs of aging and experience fatigue that is often considered normal for this age group. The entire CoQ10 Ubiquinol process happens on a cellular level, so it is not something that surgery or chemical prescription medications can imitate. Although the standard enzyme has been available for decades as a dietary supplement, manufactu
rers were unable to provide Ubiquinol due to extreme light and air sensitivities. This has changed, however, and Ubiquinol energy supplements are now available to the general public.

Ubiquinol Dosage

Just like many other supplements and prescription medications, CoQ10 Ubiquinol dosage varies based upon the specific individual’s needs. In most cases, Ubiquinol CoQ10 supplements work best when taken at a 200mg daily dosage for two weeks; this allows the supplement to hit a plateau concentration in the bloodstream and in the cells of the body. Once this plateau has been reached, Ubiquinol dosage of 100mg daily is the recommended dose to maintain the correct levels of the enzyme in the body. It is true that both the original enzyme can be found in certain foods, but a huge amount of these foods would have to be consumed in order to get a beneficial dose of the enzyme. With older people, especially those over the age of 50, the amount of the Q10 Coenzyme and Ubiquinol being produced in the body declines so much that no amount of food could make up for it. The proper dosage of Ubiquinol supplements over an extended period can make these people feel and look younger and more e
nergetic. Ubiquinol supplements come in a pill form, which is a stable and reduced form of the standard Coenzyme Q10 supplements many people are used to taking. Over the years, scientists have developed a very effective way of packaging these pills so that they are not affected by light and air.

Ubiquinol Side Effects and Interactions

There are very few Ubiquinol side effects that have been reported in clinical studies with multiple Ubiquinol preparations. Headache, nausea and general abdominal discomfort were reported in a very small group of people, but these side effects very closely mimicked those experienced by control groups taking a placebo. There were very few reports of significant allergic reactions, but these are often associated with the delivery methods instead of the Ubiquinol itself. People taking the normal enzyme supplements reported mild CoQ10 side effects like nausea and abdominal pain more often than those using Ubiquinol. Although Ubiquinol is categorized as ‘generally safe’ by most medical professionals, there are some drug interactions that patients should be aware of. People taking insulin should be aware that Ubiquinol has the potential to lower blood sugar, so dosages may need to be adjusted. The same thing exists for those taking medications to control high blood pressure; Ub
iquinol has been shown to lower blood pressure significantly in some individuals. For cancer patients undergoing chemotherapy or radiation treatments, Ubiquinol has been shown to reduce the effectiveness of these. The CoQ10 side effects are very much the same as Ubiquinol in these settings.

Benefits of Ubiquinol

When the Q10 Coenzyme is used within the body to produce Ubiquinol, the uses for this substance are truly endless. First and foremost, it gives the body basic cellular energy that is needed for almost every single function. Heart health, brain health and the optimal functioning of almost every other organ are completely dependent upon the proper levels of Ubiquinol. As part of the natural aging process, the body’s cells slowly start making less and less of this enzyme; this means the body is unable to produce enough Ubiquinol to fight free radicals or prevent fatigue. When people choose to start taking Ubiquinol supplements, they are helping their bodies in a number of ways. First, the levels of Ubiquinol in the body are greatly increased after a period of a few days. This means that the body can begin fighting off the free radicals that cause aging and cancer much more efficiently. In its natural state, the Q10 coenzyme is found in the highest concentrations in the heart m
uscle and this contributes greatly to heart health. With the proper amounts of energy at the cellular level, the heart is able to pump blood more efficiently. This reduces the odds of contracting several forms of heart disease. In addition, Ubiquinol gives many people energy that they may not have noticed before. This is not a stimulant effect, however; most people report it as a noticeable lack of the fatigue that they often feel on a daily basis. Finally, people taking statin drugs for high cholesterol should always be instructed to take Ubiquinol when possible. The statin medications are designed to reduce the concentration of bad cholesterol in the liver, thereby reducing the amount in the bloodstream and ultimately in the blood vessels of the heart. Although statin drugs are very good at doing this, they also greatly reduce the amount of the enzyme found in the liver. This causes the liver to function at a less than optimal level. Ubiquinol is a non-selective supplement;
it will concentrate in the body only where it is needed and will not over-concentrate elsewhere. This means that the supplement can replace the lost natural Ubiquinol that statin drugs take away from the liver.

Free Radicals and Ubiquinol

With all of the talk about free radicals, many people are aware they exist but are not sure exactly what they are. In order to understand how free radicals interact with both normal human cells and antioxidants, it is important to understand some basic properties about cells, atoms and molecules. The human body is comprised of trillions of cells, each of these cells is made from molecules, and these molecules are made up of atoms that are joined together by very specific chemical bonds. Atoms themselves are comprised of a nucleus, electrons, protons and neutrons. The number of protons in the core of the atom determines the number of electrons that will surround the atom. These electrons are the basis for the chemical reactions that hold molecules together. Now, any substance that is completely full of electrons tends not to get involved in any kind of chemical bonding and is considered inert. Free radicals, on the other hand, are missing some of their electrons. They ‘steal
’ electrons from any atom they bump into, including electrons from the atoms that make up living human cells. Once the free radical has stolen electrons from these atoms, they become free radicals in turn. The entire process continues until so many atoms are affected that the entire cell breaks down. This leads to premature aging, illness and even cancer. Antioxidants like Ubiquinol can help save the body’s atoms from the damaging effects of free radicals by effectively seeking them out and donating their own electrons. Since these antioxidants are not necessary for the composition of human cells, there is no harm to the body. This is why antioxidants are so important in the human body; in essence, they protect human cells from being attacked and invaded by free radicals.

Ubiquinol, The Heart, and Other Organs

Many people with heart conditions can reap huge benefits from Ubiquinol, and this is because Ubiquinol helps the heart cells produce more energy. When the concentrations of CoQ10 Ubiquinol were measured in young people and those taking daily supplements, researchers found that the highest levels of Ubiquinol were found in the cells in and around the heart. This makes sense, considering that the heart is the hardest working muscle in the entire body. People suffering from congestive heart failure, murmurs and palpitations often do not realize that this is partly because the heart simply is not strong enough to perform its job. Supplementing with Ubiquinol is not a cure for any of these illnesses, but it can help the heart perform much more efficiently. When the heart is working better, it is able to pump more oxygen rich blood to other organs, and this helps them work better as well. When all of the organs in the body are working at their peak levels, other illnesses such as d
iabetes, high blood pressure, hormonal imbalances and even chemical imbalances in the brain are able to resolve on their own with less help from chemical medications. Many of the body’s organs also deal with the metabolism of foods and the digestive system, meaning that people using Ubiquinol supplements may actually lose weight as a very nice side effect. All of these things stem from the improved heart health that the use of Ubiquinol can provide.

Ubiquinol vs CoQ10 Antioxidant Properties

Although this enzyme plays a very important role within the cells of the body, it is not an antioxidant alone. When a person takes a supplement, the enzyme must be absorbed into the individual cells in order to be made into the antioxidant Ubiquinol. Although this is possible and undoubtedly helpful, this person is not going to experience the loss of fatigue and energy gain that someone taking an Ubiquinol supplement will. The Ubiquinol CoQ10 difference is so great that many people feel as if standard supplements should be removed from shelves altogether; it has been replaced and is simply outdated. The amount of energy that the body must spend in order to absorb the enzyme is almost equal to the amount of cellular energy that the body will produce, and this almost neutralizes the entire effect. This is another argument for Ubiquinol vs CoQ10; taking a pure Ubiquinol supplement is much better for the body. The cells do not need to convert the original enzyme into the antioxid
ant Ubiquinol, so there is less energy expenditure by the body and more energy gain. The antioxidants found in the Ubiquinol supplements are fat soluble right out of the package, meaning they begin fighting free radicals almost as soon as they are ingested.

Where to Buy Ubiquinol

Ubiquinol can be purchased in many different nutritional health stores, department stores, drug stores and online outlets. As with any other over the counter medication or dietary supplement, it is important to compare the inactive ingredients and the concentrations of the active ingredient. Ubiquinol ranges in price quite a bit from manufacturer to manufacturer; often this is because the actual amount of Ubiquinol in the supplement is different. The standard dosage of Ubiquinol is 200mg a day, and the supplements are available in 50mg, 100mg and 200mg preparations. The 200mg preparation is great for once-a-day dosing, but many people choose to cut back to 100mg after the first few weeks to save money. Also, Ubiquinol comes in instant release and timed release formulations. So, someone who is taking 200mg daily may choose to break that up into 4-50mg doses of an instant release formula throughout the day. The 200mg timed release option works best when taken just before bed or
just after waking, once daily. A 100mg pill can be taken in either formulation, but if taken as an instant-release tablet it should be used twice daily—every 12 hours—instead of just once. The reason for this is that Ubiquinol works best when the same amount is present in the cells around the clock.

How to Choose a Brand of Ubiquinol

Ubiquinol is a product that is only produced in a few select locations but is sold to many different manufacturers. Because of this, many manufacturers are actually selling the exact same active ingredient—it just looks different. What often varies in these supplements is the inactive ingredients; things like buffering agents and fillers are considered inactive ingredients. Many people who take dietary supplements have specific dietary needs. Some may be allergic to gluten, milk or soy products. Some manufacturers use inactive ingredients that contain these things, so people should be very careful to read the ingredients and warning labels before choosing a product. Other supplement manufacturers may use animal proteins in their capsule casings; this is something that is taboo for many vegans all over the world. Like any other product, those with specific allergies or dietary restrictions should check labels very carefully. Also, it is important to never purchase dietary su
pplements from untrusted online sources—especially when ordering from international locations. There has been a recent increase in the number of reports of vitamin and supplement fraud, and although it rarely ends in illness, the bottles are sometimes filled with sugar pills instead of actual supplements.

The Cost of Ubiquinol

The price of Ubiquinol supplements ranges based upon the manufacturer and the concentration of the active ingredient. For instance, a bottle of 90 50mg pills may cost the same as a bottle of 30 100mg pills. For most people, the average price for a month’s supply of Ubiquinol supplements is less than $75.00. Although this may seem like a lot of money to some, it is very small when compared to the amount of money being spent on chemically based prescription medications designed to treat illnesses that could easily be prevented. People suffering from certain heart conditions, high cholesterol and even chronic fatigue often find that the amount of prescription medications they purchase after starting on an Ubiquinol regimen drops significantly—often enough to completely justify the cost of the supplement.

There is no doubt that Ubiquinol is a very important supplement for anyone over the age of 30, regardless of their current health. People who are considering beginning an Ubiquinol regimen or any other supplement should always consult with a physician and pharmacist beforehand.

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